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Spotlight:

Articles of Significant Interest Selected from This Issue by the Editors
Infect. Immun. 2008 76: 3833-3834. [Full Text] [PDF] [Reprints and Permissions]  

Guest Commentary:

Arturo Casadevall and Ferric C. Fang

Descriptive Science
Infect. Immun. 2008 76: 3835-3836. [Full Text] [PDF] [Reprints and Permissions]  

Minireviews:

John H. White

Vitamin D Signaling, Infectious Diseases, and Regulation of Innate Immunity
Infect. Immun. 2008 76: 3837-3843. [Full Text] [PDF] [Reprints and Permissions]  

Molecular Pathogenesis:

Bethany K. Boardman, Ming He, Zhiming Ouyang, Haijun Xu, Xiujuan Pang, and X. Frank Yang

Essential Role of the Response Regulator Rrp2 in the Infectious Cycle of Borrelia burgdorferi
Infect. Immun. 2008 76: 3844-3853. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Dionysios Liveris, Vishwaroop Mulay, Sabina Sandigursky, and Ira Schwartz

Borrelia burgdorferi vlsE Antigenic Variation Is Not Mediated by RecA
Infect. Immun. 2008 76: 4009-4018. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Alejandro F. Alice, Hiroaki Naka, and Jorge H. Crosa

Global Gene Expression as a Function of the Iron Status of the Bacterial Cell: Influence of Differentially Expressed Genes in the Virulence of the Human Pathogen Vibrio vulnificus
Infect. Immun. 2008 76: 4019-4037. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Chih-Cheng Tsou, Chuan Chiang-Ni, Yee-Shin Lin, Woei-Jer Chuang, Ming-T. Lin, Ching-Chuan Liu, and Jiunn-Jong Wu

An Iron-Binding Protein, Dpr, Decreases Hydrogen Peroxide Stress and Protects Streptococcus pyogenes against Multiple Stresses
Infect. Immun. 2008 76: 4038-4045. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Marta Biedzka-Sarek, Hanna Jarva, Heidi Hyytiäinen, Seppo Meri, and Mikael Skurnik

Characterization of Complement Factor H Binding to Yersinia enterocolitica Serotype O:3
Infect. Immun. 2008 76: 4100-4109. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sreedhar R. Nallapareddy, Kavindra V. Singh, Pablo C. Okhuysen, and Barbara E. Murray

A Functional Collagen Adhesin Gene, acm, in Clinical Isolates of Enterococcus faecium Correlates with the Recent Success of This Emerging Nosocomial Pathogen
Infect. Immun. 2008 76: 4110-4119. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sreedhar R. Nallapareddy, Kavindra V. Singh, and Barbara E. Murray

Contribution of the Collagen Adhesin Acm to Pathogenesis of Enterococcus faecium in Experimental Endocarditis
Infect. Immun. 2008 76: 4120-4128. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joerg Overhage, Andrea Campisano, Manjeet Bains, Ellen C. W. Torfs, Bernd H. A. Rehm, and Robert E. W. Hancock

Human Host Defense Peptide LL-37 Prevents Bacterial Biofilm Formation
Infect. Immun. 2008 76: 4176-4182. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Sug-Joon Ahn, Sang-Joon Ahn, Zezhang T. Wen, L. Jeannine Brady, and Robert A. Burne

Characteristics of Biofilm Formation by Streptococcus mutans in the Presence of Saliva
Infect. Immun. 2008 76: 4259-4268. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Eleanor Russell-Goldman, Jiayong Xu, Xiaobing Wang, John Chan, and JoAnn M. Tufariello

A Mycobacterium tuberculosis Rpf Double-Knockout Strain Exhibits Profound Defects in Reactivation from Chronic Tuberculosis and Innate Immunity Phenotypes
Infect. Immun. 2008 76: 4269-4281. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Toshio Kodama, Hirotaka Hiyoshi, Kazuyoshi Gotoh, Yukihiro Akeda, Shigeaki Matsuda, Kwon-Sam Park, Vlademir V. Cantarelli, Tetsuya Iida, and Takeshi Honda

Identification of Two Translocon Proteins of Vibrio parahaemolyticus Type III Secretion System 2
Infect. Immun. 2008 76: 4282-4289. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Cellular Microbiology: Pathogen-Host Cell Molecular Interactions:

Janneth Peralta-Ramírez, J. Manuel Hernandez, Rebeca Manning-Cela, José Luna-Muñoz, Carlos Garcia-Tovar, Jean-Philippe Nougayréde, Eric Oswald, and Fernando Navarro-Garcia

EspF Interacts with Nucleation-Promoting Factors To Recruit Junctional Proteins into Pedestals for Pedestal Maturation and Disruption of Paracellular Permeability
Infect. Immun. 2008 76: 3854-3868. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Natalia Korotkova, Yuliya Yarova-Yarovaya, Veronika Tchesnokova, Nina Yazvenko, Mike A. Carl, Ann E. Stapleton, and Steve L. Moseley

Escherichia coli DraE Adhesin-Associated Bacterial Internalization by Epithelial Cells Is Promoted Independently by Decay-Accelerating Factor and Carcinoembryonic Antigen-Related Cell Adhesion Molecule Binding and Does Not Require the DraD Invasin
Infect. Immun. 2008 76: 3869-3880. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Ine Jorgensen and Raphael H. Valdivia

Pmp-Like Proteins Pls1 and Pls2 Are Secreted into the Lumen of the Chlamydia trachomatis Inclusion
Infect. Immun. 2008 76: 3940-3950. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Brooke H. Russell, Qing Liu, Sarah A. Jenkins, Michael J. Tuvim, Burton F. Dickey, and Yi Xu

In Vivo Demonstration and Quantification of Intracellular Bacillus anthracis in Lung Epithelial Cells
Infect. Immun. 2008 76: 3975-3983. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Mélanie A. M. Cortes, Julien Gibon, Nathalie K. Chanteloup, Maryvonne Moulin-Schouleur, Philippe Gilot, and Pierre Germon

Inactivation of ibeA and ibeT Results in Decreased Expression of Type 1 Fimbriae in Extraintestinal Pathogenic Escherichia coli Strain BEN2908
Infect. Immun. 2008 76: 4129-4136. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Stephen J. Forbes, Marisa Eschmann, and Nicholas J. Mantis

Inhibition of Salmonella enterica Serovar Typhimurium Motility and Entry into Epithelial Cells by a Protective Antilipopolysaccharide Monoclonal Immunoglobulin A Antibody
Infect. Immun. 2008 76: 4137-4144. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Yue Zhang, James Murtha, Margaret A. Roberts, Richard M. Siegel, and James B. Bliska

Type III Secretion Decreases Bacterial and Host Survival following Phagocytosis of Yersinia pseudotuberculosis by Macrophages
Infect. Immun. 2008 76: 4299-4310. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Bacterial Infections:

Matthias Lochner, Kathrin Kastenmüller, Michael Neuenhahn, Heike Weighardt, Dirk H. Busch, Wolfgang Reindl, and Irmgard Förster

Decreased Susceptibility of Mice to Infection with Listeria monocytogenes in the Absence of Interleukin-18
Infect. Immun. 2008 76: 3881-3890. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Lena Lövkvist, Hong Sjölinder, Rahma Wehelie, Helena Aro, Anna Norrby-Teglund, Laura Plant, and Ann-Beth Jonsson

CD46 Contributes to the Severity of Group A Streptococcal Infection
Infect. Immun. 2008 76: 3951-3958. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Hong Sjölinder, Lena Lövkvist, Laura Plant, Jens Eriksson, Helena Aro, Allison Jones, and Ann-Beth Jonsson

The ScpC Protease of Streptococcus pyogenes Affects the Outcome of Sepsis in a Murine Model
Infect. Immun. 2008 76: 3959-3966. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Monica E. Embers, Xavier Alvarez, Tara Ooms, and Mario T. Philipp

The Failure of Immune Response Evasion by Linear Plasmid 28-1-Deficient Borrelia burgdorferi Is Attributable to Persistent Expression of an Outer Surface Protein
Infect. Immun. 2008 76: 3984-3991. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Patricia A. Spears, M. Mitsu Suyemoto, Angela M. Palermo, John R. Horton, Terri S. Hamrick, Edward A. Havell, and Paul E. Orndorff

A Listeria monocytogenes Mutant Defective in Bacteriophage Attachment Is Attenuated in Orally Inoculated Mice and Impaired in Enterocyte Intracellular Growth
Infect. Immun. 2008 76: 4046-4054. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Carsten Struve, Martin Bojer, and Karen Angeliki Krogfelt

Characterization of Klebsiella pneumoniae Type 1 Fimbriae by Detection of Phase Variation during Colonization and Infection and Impact on Virulence
Infect. Immun. 2008 76: 4055-4065. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Christina K. Leverich, Guy H. Palmer, Donald P. Knowles, Jr., and Kelly A. Brayton

Tick-Borne Transmission of Two Genetically Distinct Anaplasma marginale Strains following Superinfection of the Mammalian Reservoir Host
Infect. Immun. 2008 76: 4066-4070. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Regina C. LaRocque, Bryan Krastins, Jason B. Harris, Lauren M. Lebrun, Kenneth C. Parker, Michael Chase, Edward T. Ryan, Firdausi Qadri, David Sarracino, and Stephen B. Calderwood

Proteomic Analysis of Vibrio cholerae in Human Stool
Infect. Immun. 2008 76: 4145-4151. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Seol-Hee Kim, Shin-Young Park, Yun-Jeong Heo, and You-Hee Cho

Drosophila melanogaster-Based Screening for Multihost Virulence Factors of Pseudomonas aeruginosa PA14 and Identification of a Virulence-Attenuating Factor, HudA
Infect. Immun. 2008 76: 4152-4162. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

David A. Rosen, Chia-Suei Hung, Kimberly A. Kline, and Scott J. Hultgren

Streptozocin-Induced Diabetic Mouse Model of Urinary Tract Infection
Infect. Immun. 2008 76: 4290-4298. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Host Response and Inflammation:

Benjamin K. Billips, Anthony J. Schaeffer, and David J. Klumpp

Molecular Basis of Uropathogenic Escherichia coli Evasion of the Innate Immune Response in the Bladder
Infect. Immun. 2008 76: 3891-3900. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

María de la Cruz Domínguez-Punaro, Mariela Segura, Danuta Radzioch, Serge Rivest, and Marcelo Gottschalk

Comparison of the Susceptibilities of C57BL/6 and A/J Mouse Strains to Streptococcus suis Serotype 2 Infection
Infect. Immun. 2008 76: 3901-3910. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Sarit Lilo, Ying Zheng, and James B. Bliska

Caspase-1 Activation in Macrophages Infected with Yersinia pestis KIM Requires the Type III Secretion System Effector YopJ
Infect. Immun. 2008 76: 3911-3923. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. C. Keates, S. Tummala, R. M. Peek, Jr., E. Csizmadia, B. Kunzli, K. Becker, P. Correa, J. Romero-Gallo, M. B. Piazuelo, S. Sheth, C. P. Kelly, S. C. Robson, and S. Keates

Helicobacter pylori Infection Stimulates Plasminogen Activator Inhibitor 1 Production by Gastric Epithelial Cells
Infect. Immun. 2008 76: 3992-3999. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Elizabeth J. Theve, Yan Feng, Koli Taghizadeh, Kathleen S. Cormier, David R. Bell, James G. Fox, and Arlin B. Rogers

Sex Hormone Influence on Hepatitis in Young Male A/JCr Mice Infected with Helicobacter hepaticus
Infect. Immun. 2008 76: 4071-4078. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Anna Martner, Claes Dahlgren, James C. Paton, and Agnes E. Wold

Pneumolysin Released during Streptococcus pneumoniae Autolysis Is a Potent Activator of Intracellular Oxygen Radical Production in Neutrophils
Infect. Immun. 2008 76: 4079-4087. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Celine Cosseau, Deirdre A. Devine, Edie Dullaghan, Jennifer L. Gardy, Avinash Chikatamarla, Shaan Gellatly, Lorraine L. Yu, Jelena Pistolic, Reza Falsafi, John Tagg, and Robert E. W. Hancock

The Commensal Streptococcus salivarius K12 Downregulates the Innate Immune Responses of Human Epithelial Cells and Promotes Host-Microbe Homeostasis
Infect. Immun. 2008 76: 4163-4175. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Bernt Christian Hellerud, Jørgen Stenvik, Terje Espevik, John D. Lambris, Tom Eirik Mollnes, and Petter Brandtzaeg

Stages of Meningococcal Sepsis Simulated In Vitro, with Emphasis on Complement and Toll-Like Receptor Activation
Infect. Immun. 2008 76: 4183-4189. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

R. Al-Attiyah and A. S. Mustafa

Characterization of Human Cellular Immune Responses to Novel Mycobacterium tuberculosis Antigens Encoded by Genomic Regions Absent in Mycobacterium bovis BCG
Infect. Immun. 2008 76: 4190-4198. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Joshua S. Woodworth, Sarah M. Fortune, and Samuel M. Behar

Bacterial Protein Secretion Is Required for Priming of CD8⁺ T Cells Specific for the Mycobacterium tuberculosis Antigen CFP10
Infect. Immun. 2008 76: 4199-4205. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jeffrey J. Yu, Matthew J. Ruddy, Heather R. Conti, Kanitsak Boonanantanasarn, and Sarah L. Gaffen

The Interleukin-17 Receptor Plays a Gender-Dependent Role in Host Protection against Porphyromonas gingivalis-Induced Periodontal Bone Loss
Infect. Immun. 2008 76: 4206-4213. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Roberto De Pascalis, Betsy C. Taylor, and Karen L. Elkins

Diverse Myeloid and Lymphoid Cell Subpopulations Produce Gamma Interferon during Early Innate Immune Responses to Francisella tularensis Live Vaccine Strain
Infect. Immun. 2008 76: 4311-4321. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Fungal and Parasitic Infections:

Emma T. Cadman, Asmahan Y. Abdallah, Cécile Voisine, Anne-Marit Sponaas, Patrick Corran, Tracey Lamb, Douglas Brown, Francis Ndungu, and Jean Langhorne

Alterations of Splenic Architecture in Malaria Are Induced Independently of Toll-Like Receptors 2, 4, and 9 or MyD88 and May Affect Antibody Affinity
Infect. Immun. 2008 76: 3924-3931. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Yasuyuki Goto, Darrick Carter, and Steven G. Reed

Immunological Dominance of Trypanosoma cruzi Tandem Repeat Proteins
Infect. Immun. 2008 76: 3967-3974. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Henry W. Murray

Accelerated Control of Visceral Leishmania donovani Infection in Interleukin-6-Deficient Mice
Infect. Immun. 2008 76: 4088-4091. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Renata de Bastos Ascenço Soares, Francisco J. Gomez, Célia Maria de Almeida Soares, and George S. Deepe, Jr.

Vaccination with Heat Shock Protein 60 Induces a Protective Immune Response against Experimental Paracoccidioides brasiliensis Pulmonary Infection
Infect. Immun. 2008 76: 4214-4221. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Jan M. Ehrchen, Johannes Roth, Kirsten Roebrock, Georg Varga, Wolfram Domschke, Rodney Newberry, Clemens Sorg, Carsten Müller-Tidow, Cord Sunderkötter, Torsten Kucharzik, and Thomas W. Spahn

The Absence of Cutaneous Lymph Nodes Results in a Th2 Response and Increased Susceptibility to Leishmania major Infection in Mice
Infect. Immun. 2008 76: 4241-4250. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Abraham Guerrero and Bettina C. Fries

Phenotypic Switching in Cryptococcus neoformans Contributes to Virulence by Changing the Immunological Host Response
Infect. Immun. 2008 76: 4322-4331. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

W. Douglas Fairlie, Tim P. Spurck, Joanne E. McCoubrie, Paul R. Gilson, Susanne K. Miller, Geoffrey I. McFadden, Robyn Malby, Brendan S. Crabb, and Anthony N. Hodder

Inhibition of Malaria Parasite Development by a Cyclic Peptide That Targets the Vital Parasite Protein SERA5
Infect. Immun. 2008 76: 4332-4344. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

A. Marcil, C. Gadoury, J. Ash, J. Zhang, A. Nantel, and M. Whiteway

Analysis of PRA1 and Its Relationship to Candida albicans- Macrophage Interactions
Infect. Immun. 2008 76: 4345-4358. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Donatella Pietrella, Patrizia Lupo, Anna Rachini, Silvia Sandini, Alessandra Ciervo, Stefano Perito, Francesco Bistoni, and Anna Vecchiarelli

A Candida albicans Mannoprotein Deprived of Its Mannan Moiety Is Efficiently Taken Up and Processed by Human Dendritic Cells and Induces T-Cell Activation without Stimulating Proinflammatory Cytokine Production
Infect. Immun. 2008 76: 4359-4367. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Molecular Genomics:

Ben Sidders, Chris Pirson, Philip J. Hogarth, R. Glyn Hewinson, Neil G. Stoker, H. Martin Vordermeier, and Katie Ewer

Screening of Highly Expressed Mycobacterial Genes Identifies Rv3615c as a Useful Differential Diagnostic Antigen for the Mycobacterium tuberculosis Complex
Infect. Immun. 2008 76: 3932-3939. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Kevin Dybvig, Cao Zuhua, Ping Lao, David S. Jordan, C. Todd French, Anh-Hue T. Tu, and Ann E. Loraine

Genome of Mycoplasma arthritidis
Infect. Immun. 2008 76: 4000-4008. [Abstract] [Full Text] [PDF] [Supplemental material] [Reprints and Permissions]  

Microbial Immunity and Vaccines:

Joshua K. Turner, Milton M. McAllister, John L. Xu, and Richard I. Tapping

The Resistance of BALB/cJ Mice to Yersinia pestis Maps to the Major Histocompatibility Complex of Chromosome 17
Infect. Immun. 2008 76: 4092-4099. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Greta R. Nielubowicz, Sara N. Smith, and Harry L. T. Mobley

Outer Membrane Antigens of the Uropathogen Proteus mirabilis Recognized by the Humoral Response during Experimental Murine Urinary Tract Infection
Infect. Immun. 2008 76: 4222-4231. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Peter T. Beernink, Jo Anne Welsch, Michal Bar-Lev, Oliver Koeberling, Maurizio Comanducci, and Dan M. Granoff

Fine Antigenic Specificity and Cooperative Bactericidal Activity of Monoclonal Antibodies Directed at the Meningococcal Vaccine Candidate Factor H-Binding Protein
Infect. Immun. 2008 76: 4232-4240. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

Shengqing Yu, Hang Xie, Anup Datta, Natasha Naidu, and Xin-Xing Gu

Galactose Residues on the Lipooligosaccharide of Moraxella catarrhalis 26404 Form the Epitope Recognized by the Bactericidal Antiserum from Conjugate Vaccination
Infect. Immun. 2008 76: 4251-4258. [Abstract] [Full Text] [PDF] [Reprints and Permissions]  

To see an article, click its [Full Text] link. To review many abstracts, check the boxes to the left of the titles you want, and click the 'Get All Checked Abstract(s)' button. To see one abstract at a time, click its [Abstract] link.